Drug-Induced Nutrient Depletion - Corticosteroids

Drug-induced nutrient depletion occurs when medications that we take for various health reasons block the absorption, storage, metabolism, or synthesis of

essential nutrients in the body. Over time, these depletions can lead to secondary problems. People on multiple medications may be more likely to have reduced levels of certain nutrients. Although these nutrients are in many foods, the amount of nutrients may not be sufficient, and you may need supplementation from a high-quality vitamin/supplement.

Different types of drugs can deplete different nutrients. This week we will look at corticosteroids. For a full list of drug-induced nutrient depletions, please click here.

What nutrients can be depleted with corticosteroids?

Drug Category	Drug Class Description	Drug-Induced Nutrient Depletions	Recommended Supplementation	Dietary Supplements with potential for interactions with drug or drug class
Corticosteroids Example: Prednisone	Corticosteroids are synthetic compounds that mimic the effects of hormones naturally produced in the body by adrenal glands. They are known for relieving inflammation, pain and discomfort resulting from various health conditions.	• Calcium • Magnesium	• Calcium: 500 mg daily • Magnesium: 250–400 mg daily	Use caution with the following supplements as they may interact with and/or affect effectiveness of medication. • Herbal Supplements • Licorice • St. John’s wort

At Compounding Solutions Pharmacy & Wellness, we offer a wide range of high-quality vitamins and supplements from brands like Pure Encapsulations, Thorne Health, our own private line, and more. For more information about vitamins and supplements, ask one of our knowledgeable pharmacists.

Sources:

https://www.uspharmacist.com/article/druginduced-nutrient-depletions-what-pharmacists-need-to-know

https://www.aafp.org/dam/AAFP/documents/about_us/sponsored_resources/Nature%20Made%20Handout.pdf